Material Safety Data Sheet (MSDS) - 1-Chlorobutane
Identification
Product Name: 1-Chlorobutane
Synonyms: n-Butyl chloride, Butyl chloride
Chemical Formula: C4H9Cl
CAS Number: 109-69-3
Recommended Use: Chemical intermediate, solvent, laboratory reagent
Manufacturer Information: Major global chemical suppliers, including warning and emergency contact numbers
Emergency Phone Number: Refer to local poison control or supplier hotlines
Relevant Identified Uses: Synthesis of organic compounds, component for research
Hazard Identification
Physical Hazards: Flammable liquid and vapor
Health Hazards: Causes skin irritation, eye irritation, respiratory tract irritation, may affect central nervous system
Environmental Hazards: Toxic to aquatic life with long-lasting effects
GHS Classification: Flammable liquids (Category 2), Acute toxicity (Category 4 oral and inhalation), Skin irritation (Category 2)
Signal Word: Danger
Pictograms: Flame, Exclamation mark, Environment
Hazard Statements: Highly flammable liquid and vapor, Harmful if swallowed or inhaled, Causes skin and eye irritation, Harmful to aquatic life
Precautionary Statements: Avoid release to environment, Use explosion-proof equipment, Wear protective gear
Composition / Information on Ingredients
Chemical: 1-Chlorobutane
Concentration: >99% pure
Impurities: Traces of related chlorinated butanes
CAS Number: 109-69-3
EC Number: 203-697-1
Molecular Weight: 92.57 g/mol
First Aid Measures
General Advice: Seek medical attention in all cases of overdose or exposure
Inhalation: Move person to fresh air, keep airway open, monitor for difficulty breathing, supply oxygen if available, call for emergency help
Skin Contact: Remove contaminated clothing, wash skin thoroughly with soap and water for at least 15 minutes, do not reuse contaminated clothing until washed
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses, continue rinsing, seek medical advice promptly
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical attention, monitor for difficulty swallowing or breathing
Fire-Fighting Measures
Suitable Extinguishing Media: Alcohol-resistant foam, dry chemical, carbon dioxide, water spray (to cool containers)
Unsuitable Extinguishing Media: Direct water jet (will spread flammable liquid)
Specific Hazards: Vapors may travel, form explosive mixtures with air, may produce hydrogen chloride, carbon monoxide, carbon dioxide on combustion
Firefighter Protective Equipment: Full protective clothing, self-contained breathing apparatus
Special Procedures: Evacuate area, control run-off to prevent environmental contamination, use explosion-proof equipment
Accidental Release Measures
Personal Precautions: Evacuate personnel to safe area, avoid breathing vapors, ventilate area, remove ignition sources, use personal protective equipment
Environmental Precautions: Prevent further leakage or spillage, avoid discharge into drains, waterways, or soil
Containment: Dike spill area, contain with inert absorbent (sand, earth)
Cleanup Methods: Collect spilled liquid in sealable containers, clean area with non-flammable absorbent, dispose of contaminated material properly
Notification Procedures: Notify authorities if substance has entered environment, adhere to local regulations
Handling and Storage
Safe Handling: Use in well-ventilated areas, avoid inhalation and skin contact, keep away from heat, sparks, open flames, wear antistatic clothing and footwear
Precautions: No smoking, do not eat, drink, or smoke during use, keep work area clean, avoid static discharge
Storage Conditions: Store in tightly closed containers in a dry, cool, well-ventilated area, away from incompatible materials such as oxidizers and strong acids, keep away from sunlight
Specific End Use: For industrial, laboratory, and research use, follow manufacturer instructions
Exposure Controls and Personal Protection
Occupational Exposure Limits: ACGIH TLV: Not established; OSHA PEL: Not established; keep exposures as low as possible
Engineering Controls: Use fume hoods or local exhaust ventilation, explosion-proof electrical equipment
Personal Protective Equipment:
- Eye/Face Protection: Chemical goggles or face shield
- Skin Protection: Chemical-resistant gloves (nitrile, neoprene), impervious clothing
- Respiratory Protection: Use respirators with organic vapor cartridges when ventilation is inadequate
Hygiene Measures: Do not eat, drink or smoke in work area, wash hands after handling, remove contaminated clothing
Physical and Chemical Properties
Appearance: Colorless liquid
Odor: Sweet, ether-like
Odor Threshold: No data available
pH: Not applicable
Melting Point/Freezing Point: -123°C
Boiling Point: 78-78.5°C
Flash Point: 6°C (closed cup)
Evaporation Rate: High (comparable to ether)
Flammability: Highly flammable liquid
Vapor Pressure: 116 mmHg at 20°C
Vapor Density: 3.2 (air = 1)
Relative Density: 0.886 at 20°C
Solubility: Insoluble in water; soluble in alcohol, ether
Partition Coefficient (n-octanol/water): log Pow 2.12
Auto-Ignition Temperature: 245°C
Decomposition Temperature: Data not available
Viscosity: Not determined
Stability and Reactivity
Chemical Stability: Stable under recommended storage conditions
Reactivity: May react violently with strong oxidizers, strong bases
Condition to Avoid: Exposure to heat, open flames, spark-generating surfaces
Incompatible Materials: Strong oxidizing agents, alkalis, alkaline earth metals, amines
Hazardous Decomposition Products: Hydrogen chloride, carbon monoxide, carbon dioxide
Polymerization: No dangerous polymerization expected
Toxicological Information
Acute Toxicity: LD50 oral (rat): 2700 mg/kg; LC50 inhalation (rat, 4h): 17,000 mg/m3
Skin Corrosion/Irritation: Causes irritation and possible chemical burns
Serious Eye Damage/Irritation: Strong irritant, may cause lacrimation, temporary vision changes
Respiratory or Skin Sensitization: No data indicating sensitization
Germ Cell Mutagenicity: Data insufficient for classification
Carcinogenicity: Not classified as a carcinogen by IARC, NTP, OSHA
Reproductive Toxicity: No data indicating reproductive toxicity
Specific Target Organ Toxicity - Single Exposure: Drowsiness, dizziness, respiratory tract irritation
Specific Target Organ Toxicity - Repeated Exposure: No known chronic effects at occupational exposure levels
Aspiration Hazard: May cause lung damage if swallowed and aspirated into lungs
Ecological Information
Ecotoxicity: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Readily decomposes in air, but not rapidly degradable in water
Bioaccumulative Potential: Moderate bioaccumulation potential, log Pow 2.12 suggests possible accumulation in aquatic species
Mobility in Soil: Low; may volatilize from surface
Other Adverse Effects: Avoid environmental exposure, toxic to some aquatic organisms
Disposal Considerations
Waste Disposal Methods: Treat as hazardous waste, use approved waste disposal contractors, incinerate with afterburner and scrubber, follow federal, state, local regulations
Product Disposal: Do not discharge product into drains, watercourses, or onto ground
Container Disposal: Empty containers retain product residue, risk of explosion or fire, do not cut or weld, recycle or dispose of through licensed facility
Special Precautions: Label and secure containers, minimize environmental contamination, ensure destruction is complete
Transport Information
UN Number: UN1127
Proper Shipping Name: 1-Chlorobutane
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Environmental Hazards: Marine pollutant
Special Precautions for User: Keep containers upright, secure during transit, avoid ignition sources
Transport Labels: Flammable Liquid, Marine Pollutant
Additional Requirements: Comply with ADR/RID (Europe), IMDG (Sea), IATA (Air) regulations
Regulatory Information
Safety, Health, and Environmental Regulations: Subject to TSCA (US), REACH (EU), CEPA (Canada), and applicable national chemical inventories
Hazard Symbols: F (Highly Flammable), Xn (Harmful), N (Dangerous for the environment)
SARA Title III (USA): Not identified as an Extremely Hazardous Substance
DSL/NDSL (Canada): Listed
WHMIS Classification: B2 - Flammable Liquid, D2B - Toxic
California Proposition 65 Status: Not listed as a known carcinogen or reproductive toxicant
Other National Regulations: Observe occupational exposure regulations, labeling and packaging rules according to country
Labelling Requirements: Include hazard pictograms, signal words, hazard statements on container
